Name: AFVP - A Realistic Ventricular Rhythm Model During AF
Published: Aug. 9, 2007
License: https://opendatacommons.org/licenses/by/index.html

Software Open Access

Published: Aug. 9, 2007. Version: 1.0.0

AFVP - A Realistic Ventricular Rhythm Model During AF (Aug. 9, 2007, midnight)

AF-VP, a model for generating RR intervals in atrial fibrillation, has been contributed to PhysioNet.

Please include the standard citation for PhysioNet: (show more options)
Goldberger, A., Amaral, L., Glass, L., Hausdorff, J., Ivanov, P. C., Mark, R., ... & Stanley, H. E. (2000). PhysioBank, PhysioToolkit, and PhysioNet: Components of a new research resource for complex physiologic signals. Circulation [Online]. 101 (23), pp. e215–e220.

APA	Goldberger, A., Amaral, L., Glass, L., Hausdorff, J., Ivanov, P. C., Mark, R., ... & Stanley, H. E. (2000). PhysioBank, PhysioToolkit, and PhysioNet: Components of a new research resource for complex physiologic signals. Circulation [Online]. 101 (23), pp. e215–e220.
MLA	Goldberger, A., et al. "PhysioBank, PhysioToolkit, and PhysioNet: Components of a new research resource for complex physiologic signals. Circulation [Online]. 101 (23), pp. e215–e220." (2000).
CHICAGO	Goldberger, A., L. Amaral, L. Glass, J. Hausdorff, P. C. Ivanov, R. Mark, J. E. Mietus, G. B. Moody, C. K. Peng, and H. E. Stanley. "PhysioBank, PhysioToolkit, and PhysioNet: Components of a new research resource for complex physiologic signals. Circulation [Online]. 101 (23), pp. e215–e220." (2000).
HARVARD	Goldberger, A., Amaral, L., Glass, L., Hausdorff, J., Ivanov, P.C., Mark, R., Mietus, J.E., Moody, G.B., Peng, C.K. and Stanley, H.E., 2000. PhysioBank, PhysioToolkit, and PhysioNet: Components of a new research resource for complex physiologic signals. Circulation [Online]. 101 (23), pp. e215–e220.
VANCOUVER	Goldberger A, Amaral L, Glass L, Hausdorff J, Ivanov PC, Mark R, Mietus JE, Moody GB, Peng CK, Stanley HE. PhysioBank, PhysioToolkit, and PhysioNet: Components of a new research resource for complex physiologic signals. Circulation [Online]. 101 (23), pp. e215–e220.

Software Description

AFVP generates a synthesized beat-to-beat interval sequence of ventricular excitations with a realistic structure observed during AF. The AV junction (AVJ) is treated as a lumped structure characterized by refractoriness and automaticity. Bombarded by random AF impulses, the AVJ can also be invaded by the VP-induced retrograde wave. The model includes bi-directional conduction delays in the AVJ and ventricle. Both refractory period and conduction delay of the AVJ are dependent upon its recovery time. The electrotonic modulation by blocked impulses is also considered in the model. With proper parameter settings, the model can account for most principal statistical properties of the RR intervals during AF.

Contributors

AFVP was contributed to PhysioNet by Jie Lian, Dirk Müssig, and Volker Lang, all from Micro Systems Engineering, Inc., a subsidiary of Biotronik GmbH. The code is freely available under the GNU GPL (General Public License), and can be downloaded as a single gzip-compressed tar archive, afvp.tar.gz, or as individual files.

References

The routines used by AFVP are described in

Lian J., Müssig D., Lang V. Computer Modeling of Ventricular Rhythm During Atrial Fibrillation and Ventricular Pacing [external link, subscription required] IEEE Transactions on Biomedical Engineering 53(8): 1512-1520; 2006.

Lian, J., Clifford, G.D., Muessig, D. and Lang, V., Open source model for generating RR intervals in atrial fibrillation and beyond. BioMedical Engineering OnLine 6:9, doi:10.1186/1475-925X-6-9; 2007.

Of related interest is the set of RR interval generators entered in the PhysioNet/Computers in Cardiology Challenge 2002. These C-code algorithms were attempts to address the questions: Can you construct a simulation of the RR interval time series spanning a full 24 hours with sufficient verisimilitude to be taken as real? Can you classify a mixed set of real and simulated RR interval time series?

Access

Access Policy:
Anyone can access the files, as long as they conform to the terms of the specified license.

License (for files):
Open Data Commons Attribution License v1.0

Discovery

Topics:
interbeat rr interval simulation

Corresponding Author

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Files

Total uncompressed size: 95.1 KB.

Access the files

Download the files using your terminal:

wget -r -N -c -np https://physionet.org/files/afvp/1.0.0/

Download the files using AWS command line tools:

aws s3 sync --no-sign-request s3://physionet-open/afvp/1.0.0/ DESTINATION

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Name	Size	Modified
afvp
afvp.tar.gz (download)	14.6 KB	2019-04-12
flow.png (download)	24.9 KB	2019-04-12

AFVP - A Realistic Ventricular Rhythm Model During AF

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