Safety and Preliminary Efficacy of Intranasal Insulin for Cognitive Impairment in Parkinson Disease and Multiple System Atrophy 1.0
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Study_No | Group | Pharmacy | Disease | Disease_Dur | Age | Gender | Ethnicity | updrs1_base | updrs1_tre1 | updrs2_base | updrs2_tre1 | updrs3_base | updrs3_tre1 | brady_base | brady_tre1 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | excluded | -99 | |||||||||||||
2 | 0 | 1-PD | PD | 3 | 79 | 1 | w | 15 | 9 | 14 | 11 | 32 | 24 | 13.5 | 11 |
3 | 1 | 2-PD | PD | 9 | 64 | 1 | w | 9 | 9 | 15 | 15 | 23 | 23 | 5 | 5 |
4 | 0 | 3-PD | PD | 5 | 53 | 2 | w | 15 | 15 | 13 | 13 | 26 | 23 | 7 | 7 |
5 | 1 | 4-PD | PD | 17 | 71 | 1 | a | 16 | 16 | 23 | 23 | 23 | 23 | 6 | 6 |
6 | 0 | 5-PD | PD | 5 | 56 | 2 | w | 15 | 16 | 28 | 28 | 41 | 52 | 17 | 23 |
7 | 0 | 6-PD | PD | 7 | 66 | 2 | w | 8 | 14 | 3 | 3 | 14 | 7 | 7 | 2 |
8 | 1 | 7-PD | PD | 6 | 66 | 1 | w | 2 | 2 | 1 | 3 | 13 | 1 | 4 | 0 |
9 | 1 | 8-PD | PD | 4 | 64 | 2 | w | 9 | 5 | 4 | 3 | 12 | 6 | 2 | 3 |
10 | 0 | 9-PD | PD | 3 | 56 | 1 | w | 11 | 10 | 19 | 16 | 25 | 41 | 13 | 17 |
11 | 1 | 10-PD | PD | 4 | 65 | 2 | w | 12 | 12 | 31 | 32 | 75 | 73 | 34 | 34 |
12 | 1 | 11-PD | PD | 2 | 60 | 1 | w | 11 | 6 | 7 | 4 | 35 | 23 | 17 | 8 |
13 | 0 | 12-PD | PD | 8 | 63 | 1 | w | 6 | 8 | 15 | 13 | 52 | 36 | 29 | 17 |
14 | excluded | ||||||||||||||
15 | 1 | 14-PD | PD | 10 | 66 | 1 | w | 9 | 7 | 12 | 8 | 35 | 22 | 17 | 8 |
16 | 1 | 1-MSA | MSA | 2 | 50 | 1 | w | 9 | 8 | 18 | 20 | 36 | 34 | 20 | 18 |